Phone: (011) 7541-421, 3409-301, 3409-335, 6547-293, 3409-310
E-mail: Standards sales: prodaja@iss.rs Education: iss-edukacija@iss.rs Information about standards: infocentar@iss.rs
Stevana Brakusa 2, 11030 Beograd
Main menu

SRPS EN 16418:2014

Paper and board - Determination of the cytotoxicity of aqueous extracts using a metabolically competent hepatoma cell line (HepG2)

Sep 22, 2014

General information

90.93     Sep 3, 2025

90.00    Sep 2, 2030

ISS

H006

European Norm

85.060  

English  

Buying

Published

Language in which you want to receive the document.

Scope

This European Standard specifies a test method for the laboratory assessment of the potential cytotoxic effect of paper and board intended to come into contact with foodstuffs using specifically the HepG2 cell line.
Compared to the EN 15845[1], HepG2 cells are more representative of a human oral exposure to xenobiotics, due to the presence in the cells of phase I, II and III enzymes of the metabolism.

Life cycle

NOW

PUBLISHED
SRPS EN 16418:2014
90.93 Standard confirmed
Sep 3, 2025

Related project

Adopted from EN 16418:2014